Written by : Dr.M.D.Mazumdar, MD
Invasive Lobular Carcinoma (ILC), also called Infiltrating Lobular Cancer, make up about 10% of all breast cancers diagnosed. After Invasive Ductal Breast Cancer, it is the second most common breast cancer. Invasive means that the cancer which had originally started in the lobules of the breast has broken through the basement membrane of the lobules and invaded the surrounding tissue.
Compared to IDC, ILC tends to be larger in size at the time of diagnosis. It is also more likely to be estrogen and progesterone receptor positive. Spread to the gastrointestinal tract and ovary is also commoner than IDC.
It is common for lobular breast cancer to be diagnosed in both the breasts at the same time. If the condition occurs in only one breast, there is a high risk of it developing in the other breast in time.
Invading cells of ILC tend to break out of the main tumor in single file ('indian style') and spread through the breast in a web like pattern. They do not cause much response from the healthy cells - nether an inflammatory nor a scarring response as is seen in IDC. So a discrete mass or lump is not felt unless the tumor is quite large.
Symptoms of Invasive Lobular Carcinoma (ILC):
Survival rates for cancer are typically calculated in terms of how many people live at least five years after their diagnosis. The average five-year survival rate for breast cancer is 90 percent and the 10 year survival rate is 83 percent.
The stage of the cancer is important when considering survival rates. For instance, if the cancer is only in the breast, the five-year rate of survival is 99 percent. If it has spread to the lymph nodes, the rate decreases to 85 percent.
Depending on the stage of breast cancer, the general 5-year survival rates for women are:
Stage 0 or 1: nearly 100 percent
Stage 2: about 93 percent
Stage 3: around 72 percent
Stage 4: approximately 22 percent
Read More :
Different Types of Breast Cancer
Diagnosis of ILC